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Causes of Knee Osteoarthritis

Osteoarthritis (OA) is a form of arthritis, an inflammatory condition that wears down the cartilage in the joint area. Without the “cushioning” effect of cartilage, the bones are left to rub against each other during movement and are unprotected against shock and friction. 

Although arthritis has many causes, OA – which is known as degenerative or wear-and-tear arthritis – is a disease that develops over time, often due to aging, overuse, or excessive stress. 

Here are some of the key factors that might put you at greater risk of developing OA. 

Excessive Stress and Overuse

The main cause of knee OA is excessive, repeated stress which leads to inflammation and cartilage damage. Some activities that can lead to OA in the long term include lifting weights, squatting, kneeling, and playing sports such as soccer and long-distance running. If you are an athlete, proper conditioning and strength training can boost muscle mass around the knee and reduce the risk of OA.  

Obesity and Excessive Weight

Over the past 100 years, knee osteoarthritis has doubled in prevalence, growing alongside obesity rates and the aging population. Today, carrying excessive weight or having a BMI of 30 or more is considered to be a major risk factor for OA. Maintaining a healthy weight can help you delay the onset of degenerative joint diseases and ease the symptoms of knee OA. 

A New or Old Knee Injury

New and old knee injuries, including fractures, sprains, strains, and tendon or ligament ruptures, can increase your risk of developing OA. 

Genetics and Knee Mechanics

Some common causes of OA related to anatomic and genetic factors include:

  • A medical history of OA
  • Deformed knee bones or joints
  • Genetic mutations that make you more prone to OA
  • Posture 
  • Diseases such as rheumatoid arthritis and metabolic disorders.

Age and Gender

Although age and gender are not direct causes of knee OA, you are more likely to suffer from this condition if you are female or over the age of 55.

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Symptoms of Knee Osteoarthritis

Although the symptoms of knee OA vary over time and some patients remain asymptomatic for years, this is a degenerative disease that gets worse with aging, which makes it a major cause of disability in the elderly

Here are some of the telltale signs that you should consult a knee OA specialist. 

Pain and Swelling

Cartilage and joint damage can cause inflammation, pain, swelling, and a feeling of warmth in the joint, and the symptoms get worse at night or after a period of stillness. Over time, you might also start hearing a “cracking” sound when walking or develop bone spurs in the knee area. 

Inhibited Knee Mobility and Range of Motion

OA can cause debilitating pain and impaired movements. Over time, this can impact your knee’s range of motion and ability to move freely, which can lead to stiffness, inability to bear weight, and a feeling of instability.

Regenerative Treatment Options for Knee Osteoarthritis

Currently, people with knee OA live with the condition for an average of 30 years, which makes it essential to look beyond NSAIDs, opioids, or surgery to manage pain. 

Thanks to today’s advances in regenerative orthopedic medicine, new treatments can provide the non-surgical, non-invasive, and long-term solution.

Here are the key treatment options we offer at Orthagenex. 

Super-Concentrated PRP for Knee Osteoarthritis

Orthagenex’s PRP procedures involve a refined methodology of creating super-concentrated platelet-rich plasma that is far superior to standard PRP solutions. The extraction and concentration process of platelets, performed under strict protocols, is designed to ensure a higher concentration of growth factors — 10 – 40x over baseline value. This super-concentrated PRP approach aims to optimize patient outcomes by stimulating the body’s natural healing processes. These protocols bring together advanced imaging guidance, meticulous sterile techniques, and the precise application of super-concentrated PRP to optimize the therapeutic benefits of the treatment.

Through this, Orthagenex has been able to offer treatments that not only tackle a wide array of orthopedic conditions with PRP alone, including knee arthritis. This is particularly beneficial for patients seeking non-invasive treatments for joint and soft tissue injuries and conditions.

Bone Marrow Concentrate Stem Cell Injections for Knee Arthritis

At Orthagenex, advanced technologies and procedures are leveraged to address various orthopedic conditions, including the pioneering use of Bone Marrow Concentrate (BMC) injections. This innovative technique centers around the precise delivery of bone marrow concentrate containing stem cells into the injured area or damaged tissue. This is achieved by using imaging guidance by MSK ultrasound and fluoroscopy, which ensures a high degree of accuracy in the procedure. The result is an enhancement of the body’s natural healing processes, stimulating the repair of damaged tissues.

Patients undergoing Bone Marrow Concentrate injections at Orthagenex benefit from non- invasive procedures that require very little downtime. This is a significant advantage over traditional surgeries, which often lead to long, painful rehabilitation periods to restore joint strength and mobility. The bone marrow concentrate injections provided at Orthagenex aim to help patients avoid these arduous recovery periods.


Improve Your Knee Health With A Custom Treatment Journey 

Regenerative orthopedic techniques such as BMA and PRP can help you manage OA pain in the long term without the need to resort to opioids and NSAIDs. What’s more, when used in the early stages of knee OA, regenerative treatment can keep at bay the need for surgery. 

If you are ready to take the right step to support your knee health, get started by getting in touch with the team at Orthagenex.

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Powder Springs, GA | New Lenox, IL

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